Liver Melanomacrophages and Gluthation S-Transferase Activity in Leptodactylus chaquensis (ANURA, LEPTODACTYLIDAE) as Biomarkers of Oxidative Stress Due to Chlorpyrifos Exposition

We quantified and compared the hepatic melanomacrophage (MM) and glutathione S-transferase (GST) enzyme activity (two oxidative stress biomarkers) in the liver of Leptodatylus chaquensis adults (Anura, Leptodactylidae) collected in a rice field (CA) in San Javier department, Santa Fe (Argentina), seven days after the application of chlorpyrifos and in a reference site (SR). The histological analysis revealed a significant amount (p = 0.028) and area occupied by MM (p = 0.017) in livers of CA compared to SR. Furthermore, a significant inhibition of GST activity was recorded in the CA frogs compared to the SR (p = 0.030). The histopathological and enzymatic effects provide evidences of ecotoxicological risk for anurans in rice field with CPF application. 

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Bibliographic Details
Main Authors: Huespe, Ivan, Cabagna-Zenklusen, Mariana, Curi, Lucila Marilén, Peltzer, Paola, Attademo, Maximilano Andres, Villafañe, Noelia, Lajmanovich, Rafael Carlos
Format: Digital revista
Language:spa
Published: Universidad Nacional de Colombia - Sede Bogotá - Facultad de Ciencias - Departamento de Biología 2017
Online Access:https://revistas.unal.edu.co/index.php/actabiol/article/view/60823
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