Case report: Spindle cell tumor in a canine (fibrosarcoma)

This work presents and documents the clinic case of a canine and the histopathological findings of a subcutaneous tumor (fibrosarcoma) constituted by spindle shaped cells in the cervical region, with metastasis to the pharyngo-laryngo-tracheal region. 5 years old, male, caniche, canine, was taken to the Veterinary Clinic of the Universidad de los Llanos. During the physical examination, a painless, firm, 18 x 11 cm, subcutaneous mass was found in the dorsal region of the neck. Besides, pale mucosa, increased size of retro-pharyngeal ganglia, and bilateral epiphora were observed. After euthanasia, the necropsy was performed, then tissue samples were collected, fixed in 10% buffered formalin, and sent to the animal histopathology laboratory. The samples were processed through usual methods for optic microscopy. Histopathological sections (3-4 µm) were stained with hematoxylin-eosin (H&E) and Masson’s trichrome stain. During the necropsy it was found a dorsal cervical mass apparently encapsulated, with 18x11 cm of dimension, firm, anchored to the ligament of the nape, zones with soft consistency, with red points and rugose surface. In addition, a firm, fibrous, 6 x 4 cm tumoral nodule was found in the pharyngo-laryngo-tracheal left region. At the microscopic examination, zones with high cellularity organized in the form of fascicles were observed, with pleomorphic hyperchromatic nuclei, spindle shaped, with 1 to 2 nucleoli and other zones with less cellularity in a fibromyxoid stroma. With the staining of Masson trichrome, 50% of the cells acquired a blue coloration, positive to the collagen fibers.

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Bibliographic Details
Main Authors: Arias, A., Quevedo, D. M., Roque, A. I., Ochoa, J. E.
Format: Digital revista
Language:spa
Published: Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina Veterinaria y de Zootecnia 2022
Online Access:https://revistas.unal.edu.co/index.php/remevez/article/view/103267
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