Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
Abstract: Brain injury constitutes a disabling health condition of several etiologies. One of the major causes of brain injury is hypoxia-ischemia. Until recently, pharmacological treatments were solely focused on neurons. In the last decades, glial cells started to be considered as alternative targets for neuroprotection. Novel treatments for hypoxia-ischemia intend to modulate reactive forms of glial cells, and/or potentiate their recovery response. In this review, we summarize these neuroprotective strategies in hypoxia-ischemia and discuss their mechanisms of action.
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| Main Authors: | , , , , |
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| Format: | Artículo biblioteca |
| Language: | eng |
| Published: |
Bentham Science Publishers
2017
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| Subjects: | NEUROPROTECCION, HIPOXIA, TRATAMIENTO FARMACOLOGICO, CELULAS GLIALES, DAÑO CEREBRAL, |
| Online Access: | https://repositorio.uca.edu.ar/handle/123456789/14724 |
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