Partial reversal of striatal damage by palmitoylethanolamide administration following perinatal asphyxia

Partial reversal of striatal damage by palmitoylethanolamide administration following perinatal asphyxia

Abstract: Perinatal asphyxia (PA) is a clinical condition brought by a birth temporary oxygen deprivation associated with long-term damage in the corpus striatum, one of the most compromised brain areas. Palmitoylethanolamide (PEA) is a neuromodulator well known for its protective effects in brain injury models, including PA, albeit not deeply studied regarding its particular effects in the corpus striatum following PA. Using Bjelke et al. (1991) PA model, full-term pregnant rats were decapitated, and uterus horns were placed in a water bath at 37 C for 19 min.

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Bibliographic Details
Main Authors: Udovin, Lucas Daniel, Kobiec, Tamara, Herrera, María Inés, Toro-Urrego, Nicolás, Kölliker Frers, Rodolfo, Kusnier, Carlos Federico, Ramos Hryb, Ana Belén, Luaces, Juan Pablo, Otero Losada, Matilde, Capani, Francisco
Format: Artículo biblioteca
Language:eng
Published: Stefano Comai. Universidad de Padua, Italia 2020
Subjects:ASFIXIA PERINATAL, NEURONAS, NEUROPSICOLOGIA, NEURODEGENERACION, NEUROPROTECCION, PALMITOILETANOLAMIDA,
Online Access:https://repositorio.uca.edu.ar/handle/123456789/11312
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https://repositorio.uca.edu.ar/handle/123456789/11312

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