Does pregabalin improve sleep disorders in fibromyalgia?

ABSTRACT BACKGROUND AND OBJECTIVES: Fibromyalgia is a chronic generalized pain syndrome accompanied by somatic symptoms, mainly represented by sleep disorders. Pregabalin is the main agent among pharmacological treatments. CONTENTS: An electronic search was performed in the databases Lilacs, Pubmed/Medline, Scielo and ScienceDirect. The keywords used in English and Portuguese were “fibromyalgia”; “sleep disorder”, “treatment”; “pregabalin”; “medicine”; “fibromialgia”; “distúrbios do sono”, “tratamento”; “pregabalina”; “fármacos”. Only articles of literature review, systematic review, meta-analysis and randomized clinical studies published between October 1992 and May 2018 were included. CONCLUSION: Pregabalin is efficient and safe in the management of sleep disorders in patients with fibromyalgia because it reduces the number of awakenings and increases sleep duration.

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Bibliographic Details
Main Authors: Poluha,Rodrigo Lorenzi, Grossmann,Eduardo
Format: Digital revista
Language:English
Published: Sociedade Brasileira para o Estudo da Dor 2018
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2595-31922018000200163
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