Low dose nivolumab in metastatic mucosal melanoma: a case report

Abstract We present the case of a 77-year-old man with metastatic mucosal melanoma, unable to afford standard doses of immunotherapy, who was treated with nivolumab at a lower dose of 0.5 mg/kg every 2 weeks. Drug activity was demonstrated through both objective tumor response and an immune-related adverse event. This suggests that a lower dose of nivolumab could be a viable alternative for patients with advanced mucosal melanoma at a high risk of treatment-related financial toxicity. Further research is needed to evaluate the efficacy of lower doses of immunotherapy, including its impact on long term outcomes.

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Bibliographic Details
Main Authors: Meraz-Brenez,Andrés, Navarrete-Reyes,Ana P., Ignacio-Álvarez,Eleazar, Ramírez-Anguiano,Georgina J., Verduzco-Aguirre,Haydee C.
Format: Digital revista
Language:English
Published: Sociedad Mexicana de Oncología A.C. 2023
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2565-005X2023000300140
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