Evaluation of sialic acid concentrations and its association with the use of hormonal contraceptives

Abstract Objective: To evaluate the relationship between the use of HC and the concentration of Sialic acid (CSA) detected in the saliva of 120 women from San Luís Potosí, Mexico. Methods: Three groups were evaluated control group, HC intake shorter than 4 years, and HC intake longer than 4 years. A questionnaire was applied, anthropometric measures were taken, and collection of saliva samples was carried out. The samples were analyzed with Raman-SERS, for which silver nanoparticles were synthesized, and the measurement of SA was held. Results: The concentrations were divided into three SA groups normal (≤ 4 mg/dL), risk (> 4-7 mg/dL), and altered(> 7 mg/dL). The maximum CSA was detected, which was 9.2 mg/dL. All the volunteers who used the intrauterine system (IUS) and most of the ones who used the pills and subdermal implant (SI) presented risk and altered concentrations. Conclusions: That there is an association between the HC and the CSA, presenting a higher concentration, those volunteers who used IUS, contraceptive pills, and SI.

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Bibliographic Details
Main Authors: Rodríguez-López,Andrea G., Córdova-Serrano,Mónica L., González-Bolaños,Ana L., Téllez-Blanco,Karen B., Marín-Jaureguí,Laura S., Santoyo-Treviño,María José, Hernández-Arteaga,Aida C.
Format: Digital revista
Language:English
Published: Sociedad Mexicana de Oncología A.C. 2022
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2565-005X2022000300089
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