Physical Activity and Incidence of Atrial Fibrillation - Systematic Review and Meta-Analysis

Abstract Background: The relationship between exercise and atrial fibrillation (AF) is controversial. Objectives: To analyze the effects of physical activity on the incidence of atrial fibrillation using systematic review and meta-analysis. Methods: Systematic review and meta-analysis of studies that relate physical exercise and atrial fibrillation. The following databases were searched: PubMed, BVS Saúde and Cochrane. The following descriptors were used: "atrial fibrillation", "exercise", "physical activity" and "exercise therapy". All prospective, retrospective, cross-sectional and cohort studies were investigated. All statistical analyzes were provided using Review Manager 5.3 to provide the mean difference (MD) and relative risk (RR) ratio with 95% confidence intervals (95% CI). The statistical method of heterogeneity index was used to assess heterogeneity. Level of significance was 5%. Results: Combined analysis of 11 studies totaling 276,323 participants aged between 12 and 90 years did not suggest a significant increase in AF in individuals submitted to physical exercise (RR = 0.914, 95% CI = 0.833-1.003, heterogeneity: p < 0.001). Conclusions: Physical exercise, lato sensu, without stratification by intensity, sex or age does not seem to be associated with an increase of atrial fibrillation.

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Bibliographic Details
Main Authors: Garlipp,Daniel Carlos, Guimaraes,Raphael Boesche, Savaris,Simone Louise, Froemming Junior,Clovis, Dutra,Oscar, Leiria,Tiago Luiz Luz
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Cardiologia 2019
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472019000400384
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