Solitary Fibrous Tumor of the Breast: A Rare Case
Abstract A solitary fibrous tumor (SFT) is a rare neoplasm often found in the pleura. Breast SFT is extremely rare, with just a few cases reported in the literature. The 49-year-old woman presented with a palpable lump in right breast. Mammography revealed an oval circumscribed mass which on ultrasound corresponded to a well-defined hypoechoic nodule. The imaging findings are not pathognomonic, therefore definitive diagnosis requires histological examination and immune-histochemical analysis. Histologically, neoplastic cells may adopt spindle to ovoid morphology, and the growth pattern is variable. In the immune-histochemical study, the tumor cells are characterized by strong and diffuse positivity for CD34 and STAT-6. In conclusion, breast SFT is rare. Histology may show overlapping characteristics with other conditions, with STAT-6 being a sensitive and specific marker that makes the definitive diagnosis. Surgical resection is the gold standard treatment. Although most have a benign and indolent clinical course, long-term follow-up is recommended.
| Main Authors: | , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedade Portuguesa de Radiologia e Medicina Nuclear
2022
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| Online Access: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2183-13512022000100029 |
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