Proprioceptive deficits in Parkinson's disease: from clinical data to animal experimentation

Parkinson's disease (PD) is characterized by the manifestation of akinesia, slowness to initiate movement, muscle rigidity, and tremors. However, recent evidence indicates that this pathology also causes alterations in proprioception. Disturbances in proprioceptive mechanisms directly affect postural control and the ability to calculate the velocity and amplitude of movement, suggesting that these alterations are related to the motor symptoms of PD. This article reviews the clinical data on these symptoms and presents evidence of a connection between proprioceptive deficits and the physiology of PD. The identification of proprioceptive impairments in different forms of Parkinsonism can provide valuable clues on the physiopathology of proprioception in idiopathic PD.

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Bibliographic Details
Main Authors: Ribeiro,Letícia, Souza,Tadeu Mello e, Bizarro,Lisiane, Oliveira,Alcyr
Format: Digital revista
Language:English
Published: Pontificia Universidade Católica do Rio de Janeiro 2011
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000200009
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