A rare case of giant verruciform xanthoma in the palate

Verruciform xanthoma represents a rare disease of unknown etiology that typically affects the oral mucosa. In most cases, it is asymptomatic and characterized by a well demarcated elevation with irregular or papillary surface. The gums are the most affected oral site, and the lesion is usually less than 2 cm in diameter. The aim of this study is to report a rare case of an extensive verruciform xanthoma in the hard palate and gums of a 55-year-old male. Clinically, the well delimitated, reddish, elastic lesion measuring approximately 2.8 X 1.5 cm had a slightly granular surface. Histopathological analysis found proliferative epithelial activity with evident papillomatosis, parakeratosis, and large epithelial ridges. Xanthomatous cells with clear, vacuolated cytoplasm were detected in the lamina propria. The patient has been disease free for 18 months. According to an extensive research in the PubMed, MEDLINE, and Lilacs databases, this paper describes one of the most extensive cases of verruciform xanthoma reported in the literature.

Saved in:
Bibliographic Details
Main Authors: ROSA,Eduardo Augusto, AMORIM,Rivadávio Fernandes Batista de
Format: Digital revista
Language:English
Published: Faculdade São Leopoldo Mandic 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1981-86372014000100077
Tags: Add Tag
No Tags, Be the first to tag this record!