Biomarker responses of cardiac oxidative stress to high intensity interval training in rats

Abstract Aim: The present study aimed to verify the cardiac oxidative stress biomarker responses to high-intensity interval training (HIIT) in rats. Methods: Sixteen male Wistar rats weighing 250 to 300 g were equally divided into two groups (8 animals/group): sedentary control (SC) and trained group (HIIT). The exercise protocol consisted of high-intensity swimming (14% of body weight, 20 s of activity with 10 s of pause performed 14 times) which was performed for 12 consecutive days. Results: The cardiac tissue concentrations of malondialdehyde and carbonylated proteins showed no significant changes; on the other hand, hydroperoxide levels were higher in the HIIT group than in the SC group. The activities of superoxide dismutase, catalase, and glutathione peroxidase enzymes and the levels of reduced glutathione and sulfhydryl remained unchanged. Conclusion: It is possible to conclude that short-term high-intensity interval training induces changes in the cardiac oxidative stress biomarker but with no effect on the antioxidant enzymes.

Bibliographic Details

Main Authors:	Vieira-Souza,Lúcio Marques, Santos,Jymmys Lopes dos, Marçal,Anderson Carlos, Voltarelli,Fabrício Azevedo, Aidar,Felipe José, Miguel-dos-Santos,Rodrigo, Costa,Roas de Araújo, Matos,Dihogo Gama de, Santos,Sandra Lauton, Araújo,Silvan Silva de
Format:	Digital revista
Language:	English
Published:	Universidade Estadual Paulista 2021
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-65742021000101002
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