Creutzfeldt-Jakob disease: literature review based on three case reports

ABSTRACT. Creutzfeldt-Jakob disease (CJD) is one of the transmissible spongiform encephalopathies that lead to rapidly progressive dementia. CJD has a low prevalence, and the average survival is only 1 year after the onset of symptoms. As the patients with CJD develop rapidly progressive dementia, associated with myoclonus, visual or cerebellar problems, pyramidal or extrapyramidal features, and akinetic mutism, the hypothesis of CJD must be raised. Classic magnetic resonance imaging (MRI) findings are hypersignals in the caudate nucleus, putamen, and cortical region. CJD must be considered a differential diagnosis of other types of dementia, and there is no effective treatment for this disease. In this article, we present a literature review based on the report of three cases of the sporadic form of this disease.

Bibliographic Details

Main Authors:	Carneiro,Amandha Alencar Maia, Esmeraldo,Mateus Aragão, Silva,David Elison de Lima e, Ribeiro,Espártaco Moraes Lima
Format:	Digital revista
Language:	English
Published:	Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2022
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642022005008202
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