Rasmussen encephalitis: an older adult presentation?

ABSTRACT. Rasmussen encephalitis (RE) is a classic disorder in the child age group, and only 10% of cases are described in adults. We bring two proven cases of RE in older adults aged over 55 years. Objective: To describe the clinical characteristics, progression, diagnostic assessment, neuropathological findings, and treatment of RE in two clinical cases of patients over 55 years of age. Furthermore, we address progressive cognitive decline as an important feature of the RE presentation in older adults in association with focal epilepsy. Methods: This is a case series from two tertiary hospitals from São Paulo – Brazil. Retrospective data were collected from one case. Results: Two male individuals aged >55 years with clinical presentation of focal epilepsy along with progressive cognitive deterioration. Conclusions: RE could be considered the cause of progressive cognitive decline in older adults, especially if focal epilepsy is described together with asymmetrical neuroimaging findings.

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Main Authors: Alvim,Ricardo Pires, Aguiar,Patrick, Amado,Daniel Kempel, Rocha,Maria Sheila Guimarães, Rodriguez,Roberta Diehl, Brucki,Sonia Maria Dozzi
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642020000400434
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spelling oai:scielo:S1980-576420200004004342020-12-07Rasmussen encephalitis: an older adult presentation?Alvim,Ricardo PiresAguiar,PatrickAmado,Daniel KempelRocha,Maria Sheila GuimarãesRodriguez,Roberta DiehlBrucki,Sonia Maria Dozzi dementia cognitive dysfunction encephalitis epilepsy ABSTRACT. Rasmussen encephalitis (RE) is a classic disorder in the child age group, and only 10% of cases are described in adults. We bring two proven cases of RE in older adults aged over 55 years. Objective: To describe the clinical characteristics, progression, diagnostic assessment, neuropathological findings, and treatment of RE in two clinical cases of patients over 55 years of age. Furthermore, we address progressive cognitive decline as an important feature of the RE presentation in older adults in association with focal epilepsy. Methods: This is a case series from two tertiary hospitals from São Paulo – Brazil. Retrospective data were collected from one case. Results: Two male individuals aged >55 years with clinical presentation of focal epilepsy along with progressive cognitive deterioration. Conclusions: RE could be considered the cause of progressive cognitive decline in older adults, especially if focal epilepsy is described together with asymmetrical neuroimaging findings.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e EnvelhecimentoDementia & Neuropsychologia v.14 n.4 20202020-12-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642020000400434en10.1590/1980-57642020dn14-040016
institution SCIELO
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country Brasil
countrycode BR
component Revista
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databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Alvim,Ricardo Pires
Aguiar,Patrick
Amado,Daniel Kempel
Rocha,Maria Sheila Guimarães
Rodriguez,Roberta Diehl
Brucki,Sonia Maria Dozzi
spellingShingle Alvim,Ricardo Pires
Aguiar,Patrick
Amado,Daniel Kempel
Rocha,Maria Sheila Guimarães
Rodriguez,Roberta Diehl
Brucki,Sonia Maria Dozzi
Rasmussen encephalitis: an older adult presentation?
author_facet Alvim,Ricardo Pires
Aguiar,Patrick
Amado,Daniel Kempel
Rocha,Maria Sheila Guimarães
Rodriguez,Roberta Diehl
Brucki,Sonia Maria Dozzi
author_sort Alvim,Ricardo Pires
title Rasmussen encephalitis: an older adult presentation?
title_short Rasmussen encephalitis: an older adult presentation?
title_full Rasmussen encephalitis: an older adult presentation?
title_fullStr Rasmussen encephalitis: an older adult presentation?
title_full_unstemmed Rasmussen encephalitis: an older adult presentation?
title_sort rasmussen encephalitis: an older adult presentation?
description ABSTRACT. Rasmussen encephalitis (RE) is a classic disorder in the child age group, and only 10% of cases are described in adults. We bring two proven cases of RE in older adults aged over 55 years. Objective: To describe the clinical characteristics, progression, diagnostic assessment, neuropathological findings, and treatment of RE in two clinical cases of patients over 55 years of age. Furthermore, we address progressive cognitive decline as an important feature of the RE presentation in older adults in association with focal epilepsy. Methods: This is a case series from two tertiary hospitals from São Paulo – Brazil. Retrospective data were collected from one case. Results: Two male individuals aged >55 years with clinical presentation of focal epilepsy along with progressive cognitive deterioration. Conclusions: RE could be considered the cause of progressive cognitive decline in older adults, especially if focal epilepsy is described together with asymmetrical neuroimaging findings.
publisher Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publishDate 2020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642020000400434
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AT amadodanielkempel rasmussenencephalitisanolderadultpresentation
AT rochamariasheilaguimaraes rasmussenencephalitisanolderadultpresentation
AT rodriguezrobertadiehl rasmussenencephalitisanolderadultpresentation
AT bruckisoniamariadozzi rasmussenencephalitisanolderadultpresentation
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