Rasmussen encephalitis: an older adult presentation?
ABSTRACT. Rasmussen encephalitis (RE) is a classic disorder in the child age group, and only 10% of cases are described in adults. We bring two proven cases of RE in older adults aged over 55 years. Objective: To describe the clinical characteristics, progression, diagnostic assessment, neuropathological findings, and treatment of RE in two clinical cases of patients over 55 years of age. Furthermore, we address progressive cognitive decline as an important feature of the RE presentation in older adults in association with focal epilepsy. Methods: This is a case series from two tertiary hospitals from São Paulo – Brazil. Retrospective data were collected from one case. Results: Two male individuals aged >55 years with clinical presentation of focal epilepsy along with progressive cognitive deterioration. Conclusions: RE could be considered the cause of progressive cognitive decline in older adults, especially if focal epilepsy is described together with asymmetrical neuroimaging findings.
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Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
2020
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oai:scielo:S1980-576420200004004342020-12-07Rasmussen encephalitis: an older adult presentation?Alvim,Ricardo PiresAguiar,PatrickAmado,Daniel KempelRocha,Maria Sheila GuimarãesRodriguez,Roberta DiehlBrucki,Sonia Maria Dozzi dementia cognitive dysfunction encephalitis epilepsy ABSTRACT. Rasmussen encephalitis (RE) is a classic disorder in the child age group, and only 10% of cases are described in adults. We bring two proven cases of RE in older adults aged over 55 years. Objective: To describe the clinical characteristics, progression, diagnostic assessment, neuropathological findings, and treatment of RE in two clinical cases of patients over 55 years of age. Furthermore, we address progressive cognitive decline as an important feature of the RE presentation in older adults in association with focal epilepsy. Methods: This is a case series from two tertiary hospitals from São Paulo – Brazil. Retrospective data were collected from one case. Results: Two male individuals aged >55 years with clinical presentation of focal epilepsy along with progressive cognitive deterioration. Conclusions: RE could be considered the cause of progressive cognitive decline in older adults, especially if focal epilepsy is described together with asymmetrical neuroimaging findings.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e EnvelhecimentoDementia & Neuropsychologia v.14 n.4 20202020-12-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642020000400434en10.1590/1980-57642020dn14-040016 |
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Alvim,Ricardo Pires Aguiar,Patrick Amado,Daniel Kempel Rocha,Maria Sheila Guimarães Rodriguez,Roberta Diehl Brucki,Sonia Maria Dozzi |
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Alvim,Ricardo Pires Aguiar,Patrick Amado,Daniel Kempel Rocha,Maria Sheila Guimarães Rodriguez,Roberta Diehl Brucki,Sonia Maria Dozzi Rasmussen encephalitis: an older adult presentation? |
author_facet |
Alvim,Ricardo Pires Aguiar,Patrick Amado,Daniel Kempel Rocha,Maria Sheila Guimarães Rodriguez,Roberta Diehl Brucki,Sonia Maria Dozzi |
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Alvim,Ricardo Pires |
title |
Rasmussen encephalitis: an older adult presentation? |
title_short |
Rasmussen encephalitis: an older adult presentation? |
title_full |
Rasmussen encephalitis: an older adult presentation? |
title_fullStr |
Rasmussen encephalitis: an older adult presentation? |
title_full_unstemmed |
Rasmussen encephalitis: an older adult presentation? |
title_sort |
rasmussen encephalitis: an older adult presentation? |
description |
ABSTRACT. Rasmussen encephalitis (RE) is a classic disorder in the child age group, and only 10% of cases are described in adults. We bring two proven cases of RE in older adults aged over 55 years. Objective: To describe the clinical characteristics, progression, diagnostic assessment, neuropathological findings, and treatment of RE in two clinical cases of patients over 55 years of age. Furthermore, we address progressive cognitive decline as an important feature of the RE presentation in older adults in association with focal epilepsy. Methods: This is a case series from two tertiary hospitals from São Paulo – Brazil. Retrospective data were collected from one case. Results: Two male individuals aged >55 years with clinical presentation of focal epilepsy along with progressive cognitive deterioration. Conclusions: RE could be considered the cause of progressive cognitive decline in older adults, especially if focal epilepsy is described together with asymmetrical neuroimaging findings. |
publisher |
Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento |
publishDate |
2020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642020000400434 |
work_keys_str_mv |
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