Infrared Irradiation-Assisted Multicomponent Synthesis of 2-Amino-3-cyano-4H-pyran Derivatives

A simple, versatile, and efficient synthesis of 4H-pyran derivative compounds is achieved via a three-component cyclocon-densation of aldehyles, malononitrile, and ethyl acetoacetate, using ammonium hydroxide as the catalyst, promoted by infrared irradiation. The present method offers several advantages, such as high yields, non hazarlous reaction conditions as well as short reaction times.

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Bibliographic Details
Main Authors: Sánchez,Arturo, Hernández,Fernando, Cruz,Paulo César, Alcaraz,Yolanda, Tamariz,Joaquín, Delgado,Francisco, Vázquez,Miguel A.
Format: Digital revista
Language:English
Published: Sociedad Química de México A.C. 2012
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1870-249X2012000200006
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