In vitro anthelmintic activity of Lippia gracilis Schauer essential oil against egg-hatching of goat gastrointestinal nematodes

ABSTRACT Since drug-resistant nematodes became a common problem in sheep and goat industries, alternative methods using natural products have emerged as a viable and sustainable anthelmintic treatment option. Here, the in vitro effect of essential oil extracted from Lippia gracilis Schauer was assessed on the hatching process of nematodes recovered from naturally infected goats. Essential oil at concentrations of 0.08% (0.008 μL/mL), 0.12% (0.012 μL/mL), and 0.16% (0.016 μL/mL) was able to induce an average inhibition of 74.7, 84 and 93%, respectively. The effective concentration required to inhibit egg hatching in 50% of eggs (EC50) was 0.03452%. Therefore, essential oil of L. gracilis showed promisor in vitro anthelmintic results against egg-hatching of goat gastrointestinal nematodes.

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Bibliographic Details
Main Authors: Souza,Anna Lopes da Costa, Rebouças,Cristina Karine de Oliveira, Albuquerque,Cynthia Cavalcanti de, Moura,Cristiane de Carvalho Ferreira Lima, Torres,Taffarel Melo, Batista,João Inácio Lopes, Bezerra,Francisco Silvestre Brilhante, Bezerra,Ana Carla Diógenes Suassuna
Format: Digital revista
Language:English
Published: Instituto Biológico 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-16572020000100405
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