Cytokine levels in pleural fluid as markers of acute rejection after lung transplantation
Our objective was to determine the levels of lactate dehydrogenase, IL-6, IL-8, and VEGF, as well as the total and differential cell counts, in the pleural fluid of lung transplant recipients, correlating those levels with the occurrence and severity of rejection. We analyzed pleural fluid samples collected from 18 patients at various time points (up to postoperative day 4). The levels of IL-6, IL-8, and VEGF tended to elevate in parallel with increases in the severity of rejection. Our results suggest that these levels are markers of acute graft rejection in lung transplant recipients.
Main Authors: | , , , , , |
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Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Pneumologia e Tisiologia
2014
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132014000400425 |
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