Update on gingival overgrowth by cyclosporine A in renal transplants

Severe gingival overgrowth is one of the most frequent side effects in renal transplant patients associated with assumption of cyclosporine A. Several associations with age, sex, dosage, duration of therapy or interval since transplantation have been hypothesized. The introduction of alternative immunosuppressant drugs have been suggested to permit better long-term transplant outcomes and a decrease in incidence of gingival overgrowth. The aim of the present paper is to summarize current knowledge regarding aetiology, pathogenesis and management of gingival overgrowth induced by Cyclosporine A.

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Bibliographic Details
Main Authors: Ciavarella,Domenico, Guiglia,Rosario, Campisi,Giuseppina, Cosola,Michele Di, Liberto,Chiara Di, Sabatucci,Antonio, Escudero,Nayra, Bascones,Antonio, Lo Muzio,Lorenzo
Format: Digital revista
Language:English
Published: Sociedad Española de Medicina Oral 2007
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1698-69462007000100005
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