Rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic symmetrical inflammatory arthropathy with potentially debilitating consequences in the early phases of the disease functional limitation is reversible; however, persistent inflammation results in irreversible structural changes and systemic effects accounting for considerable morbidity and premature mortality. This review, second of a two-part series, explores a paradigm shift in management of emphasising the pitfalls and benefit of early aggressive pharmacological therapies including the timely use of highly efficacious pharmacological innovations. Side effects, including peri-operative implications of pharmacological therapy, are discussed. These therapies are cost effective if used early and judiciously, giving hope to many patients with RA.
| Main Authors: | , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Medpharm Publications
2010
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| Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1681-150X2010000200004 |
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