Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report

This case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity againstHistoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H. capsulatum andCryptococcus neoformans. The evaluation of paucisymptomatic patients with positive results for H. capsulatum and C. neoformans could be relevant for the prevention as well as the possible evaluation of the reactivated quiescent foci. In conclusion, the associated methodology may have contributed to the monitoring endogenous reactivation of these diseases.

Bibliographic Details

Main Authors:	Dantas,Kátia Cristina, Freitas,Roseli Santos de, Garcia,Roberta Scholz Pinto, Silva,Marcos Vinícius da, Muricy,Edna Cleide Mendes, Kohara,Valdelene Sayuri, Vicentini,Adriana Pardini
Format:	Digital revista
Language:	English
Published:	Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP) 2014
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200507
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