Russell body gastritis: case report

Russell body gastritis (RBG), which can be associated with Helicobacter pylori (HP) infection, is a recently acknowledged lesion characterized by the presence of eosinophilic intracytoplasmic inclusions in plasmacytes. Herein the authors discuss the morphological aspects of a case of RBG in a male patient with clinical complaint of epigastric pain. Upper endoscopy revealed areas of erythema/edema in the antrum. As far as microscopy is concerned, a mononuclear inflammatory infiltrate was identified on the lamina propria, with plasma cells containing Schiff acid periodic (PAS) positive eosinophilic intracytoplasmic globules, which showed positive immunostaining for CD79a, CD138, and kappa/lambda light chains. HP was identified by Giemsa stains.

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Bibliographic Details
Main Authors: Cambruzzi,Eduardo, Pêgas,Karla Lais, Laus,Fernanda de Fátima
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2012
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442012000100008
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