Catalase-negative, methicillin-resistant Staphylococcus aureus as a cause of septicemia

A catalase-negative methicillin-resistant Staphylococcus aureus (MRSA) was isolated from blood, venous catheter spike and bone marrow collected from an HIV-positive man with lobar pneumonia and sepsis after ten days of hospitalization. The isolate was resistant to oxacillin (positive for penicillin-binding protein 2'), ceftriaxone, clindamycin and clarithromycin, and susceptible to vancomycin. This is the first case of septicemia due to a catalase-negative S. aureus reported in Brazil, and, to our knowledge, it is the first case of catalase-negative MRSA reported in the literature. We believe that the patient acquired the S. aureus infection within the hospital environment since it was isolated ten days after hospitalization, it was isolated in a venous catheter spike, and the antibiotic resistance profile is similar to other S. aureus isolates recovered from infections in our hospital.

Bibliographic Details

Main Authors:	Carvalho,Ana Lúcia Innaco de, Zanella,Rosemeire Cobo, Yoshikawa,Luciane Parra, Bokermann,Sérgio, Guerra,Maria Luiza L.S., Atobe,Jane Harumi, Lovgren,Marguerite
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Patologia Clínica 2003
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442003000100009
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