A mechanical approach to the growth plate behavior and chondrocytes columns organization

Abstract This study aims to explore the behavior of mechanical stimuli and their effect on growth plate shape under different physiological scenarios and loading conditions. A linear elastic, isotropic, and homogeneous model was implemented to model the epiphyseal progressive ossification and the development of the secondary ossification center. Results shed light on the role of mechanical stimulus, suggesting that maximum shear stress, hydrostatic stress, and von Mises stress may contribute to the morphological changes of the growth plate. This model is a useful tool to improve orthopedic therapies focused on pathologies that imply abnormal bone growth under abnormal mechanical conditions.

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Bibliographic Details
Main Authors: Castro-Abril,Hector, Duque Daza,Carlos A., Vaca-González,Juan Jairo, Garzon-Alvarado,Diego Alexander
Format: Digital revista
Language:English
Published: Universidad Nacional Autónoma de México, Instituto de Ciencias Aplicadas y Tecnología 2023
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1665-64232023000400631
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