Acne and diet: a review of pathogenic mechanisms

Abstract Acne is a chronic inflammatory disease of the pilosebaceous unit with multifactorial etiology. Abnormal proliferation of keratinocytes, altered sebum production, inflammation of the sebaceous follicle, and colonization by Cutibacterium acnes have been traditionally implicated. However, the diet has also been highlighted in the pathogenesis because of its direct relation with some biochemical markers and the transcription of specific genes associated with sebaceous gland activity, inflammation, and bacterial proliferation, which together promote the development of the disease, affect the severity of the condition, and modify its response to treatment.

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Bibliographic Details
Main Authors: González-Mondragón,Edgar A., Ganoza-Granados,Luciana del C., Toledo-Bahena,Mirna Eréndira, Valencia-Herrera,Adriana M., Duarte-Abdala,Mario R., Camargo-Sánchez,Karen A., Mena-Cedillos,Carlos A.
Format: Digital revista
Language:English
Published: Instituto Nacional de Salud, Hospital Infantil de México Federico Gómez 2022
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1665-11462022000200083
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