Effect of 15 consecutive HIIT sessions on the redox State in Wistar rats

ABSTRACT High-intensity interval training (HIIT) can induce oxidative stress. The main aim of this study was to evaluate the effect of 15 sessions of a HIIT protocol in Wistar rats on oxidative damage markers in different tissues (blood, muscle, liver and heart). Thus, animals weighing 250-300 g were used and randomly divided into 2 groups (n= 10): Control (CG) and animals submitted to HIIT (TG) through a swimming protocol. The results showed that HIIT increased the production of malondialdehyde (MDA) in TG animals: serum (306.75%), gastrocnemius muscle (259.2%), liver (452.6%) and heart (215%), while the concentration of sulfhydryl groups decreased: serum (40%), gastrocnemius muscle (44.7%), liver (44.6%) and heart (47.2%). Thus, it could be concluded that 15 HIIT sessions altered the redox state of Wistar rats due to increased oxidative damage markers in the analysed tissues.

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Bibliographic Details
Main Authors: Rodrigues,Josimar Camacho, Costa,Roas de Araújo, Aidar,Felipe José, Souza,Raphael Fabrício de, Brito,Ciro José, Santos,Jymmys Lopes dos, Vieira-Souza,Lucio Marques
Format: Digital revista
Language:English
Published: Edições Desafio Singular 2023
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-107X2023000300306
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