Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1

We assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to CD4 counts. Untreated patients had higher D-Ab (geometric mean of 0.62 IU/ml) than HAART-patients (geometric mean of 0.39 IU/ml). The data indicated the necessity of keeping all HIV-1 patients up-to-date with their vaccination.

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Bibliographic Details
Main Authors: Speranza,Francisco A. B., Ishii,Solange K., Thuler,Luiz C. S., Damasco,Paulo V., Hirata Jr,Raphael, Mattos-Guaraldi,Ana L., Milagres,Lucimar G.
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Microbiologia 2012
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300014
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