A suitable procedure to choose antimicrobials as controlling agents in fermentations performed by bacteria

This work evaluated the influence of nitrofurantoin, erythromycin and streptomycin at 50, 25 and 12,5% of the minimal inhibitory concentration (MIC) on maximum specific growth rate (µmax) and specific polymer accumulation rate (µPHB) of Alcaligenes eutrophus, considered resistant to those antimicrobials. Nitrofurantoin strongly affected µmax even at 50% MIC. Streptomycin moderately affected µmax only at 50%MIC. Nitrofurantoin showed the most harmful effect on µPHB when 50% MIC was applied and erythromycin was not harmful.

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Bibliographic Details
Main Authors: Oliveira,Romulo C., Gomez,José G.C., Torres,Bayardo B., Bueno Netto,Celso L., Silva,Luiziana F. da
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Microbiologia 2000
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822000000200004
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