Investigation of liver tissue and biochemical parameters of adult wistar rats treated with Arctium lappa L.

This study was carried out to evaluate the effects of Arctium lappa L. (burdock) on the liver of adult male Wistar rats as measured by light microscopy and biochemical parameters. The rats received the extract in water bottles at doses of 10 or 20 g/L daily for 40 days. There were no significant changes in the plasma levels of albumin, aspartate transaminase (AST), alanine transaminase (ALT), gamma glutamyl transferase (GGT), total protein, total cholesterol, urea, uric acid, triacylglycerol, calcium, phosphorus, chlorine and direct bilirubin. The morphological analysis did not reveal histopathological alterations in liver tissue. Both biochemical and morphological data did not indicate A. lappa toxicity.

Saved in:
Bibliographic Details
Main Authors: Predes,Fabrícia Souza, Matta,Sérgio Luis Pinto da, Monteiro,Juliana Castro, Oliveira,Tânia Toledo de
Format: Digital revista
Language:English
Published: Instituto de Tecnologia do Paraná - Tecpar 2009
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200010
Tags: Add Tag
No Tags, Be the first to tag this record!