Rosai-Dorfman disease with spontaneous resolution: case report of a child

Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child with progressive cervical lymphadenopathy associated with persistent fever and radiological findings suggestive of lymphoma. Histopathological and immunohistochemistry studies of a lymph node biopsy established the diagnosis of Rosai-Dorfman disease. Both lymphadenopathy and fever resolved spontaneously.

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Bibliographic Details
Main Authors: Lima,Felipe Barbosa, Barcelos,Pedro Samuel de Valões, Constâncio,Ana Paula Nunes, Nogueira,Cleto Dantas, Melo-Filho,Antônio Aldo
Format: Digital revista
Language:English
Published: Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular 2011
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000400018
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