Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination

CONTEXT: Sarcomatous differentiation, which represents transformation to high-grade malignancy, can occur in all histogical types of renal malignancy. CASE REPORT: The authors report on the case of a 66-year-old woman with a right renal mass that was shown to be a clear cell carcinoma. She underwent radical nephrectomy and dendritic cell vaccination and, 3.5 years later, she developed retroperitoneal pure sarcomatous recurrence of the tumor. The authors speculate that the vaccination could have played some role in this differentiation or selection of the sarcomatous component of the primary tumor.

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Bibliographic Details
Main Authors: Antunes,Alberto Azoubel, Dall’Oglio,Marcos Francisco, Barbuto,José Alexandre Marzagão, Leite,Kátia Ramos Moreira, Srougi,Miguel
Format: Digital revista
Language:English
Published: Associação Paulista de Medicina - APM 2006
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802006000300011
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