Prognosis related to staging systems for chronic lymphocytic leukemia

CONTEXT: Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder, characterized by B lymphocytic proliferation. CLL is the most frequent adult leukemia in Western countries, accounting for 25 to 30% of all white leukemic patients. OBJECTIVE: To evaluate clinical and staging characteristics in prognosis of chronic lymphocytic leukemia. DESIGN: Evaluation of clinical-staging data. SETTING: Universidade Federal de São Paulo - Escola Paulista de Medicina / Universidade de Alfenas. SAMPLE: 73 patients diagnosed from 1977 to 1994. MAIN MEASUREMENTS: Sex, ethnic origin, age, lymphadenopathy, splenomegaly, hepatomegaly, three or more areas of lymphoid enlargement, hemoglobin (g/dl), lymphocytes/mm³, Platelets/mm³ RESULTS: Mean survival of patients was 76 months, median age was 65 years, ranging from 33 to 87. Forty-four patients (60.3%) were male and 29 (39.7%) female. CONCLUSION: The Binet system determined a better prognosis than Rai.

Bibliographic Details

Main Authors:	Faria,José Roberto de, Oliveira,José Salvador Rodrigues de, Faria,Rosa Malena Delbone de, Silva,Maria Regina Regis, Goihman,Samuel, Yamamoto,Miohoko, Kerbauy,José
Format:	Digital revista
Language:	English
Published:	Associação Paulista de Medicina - APM 2000
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802000000400002
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