Abacavir-induced liver toxicity

Abstract Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine.

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Bibliographic Details
Main Authors: Pezzani,Maria Diletta, Resnati,Chiara, Di Cristo,Valentina, Riva,Agostino, Gervasoni,Cristina
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500502
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