Chronic meningitis by histoplasmosis: report of a child with acute myeloid leukemia

Meningitis is a common evolution in progressive disseminated histoplasmosis in children, and is asymptomatic in many cases. In leukemia, the impaired of the T cells function can predispose to the disseminated form. The attributed mortality rate in this case is 20%-40% and the relapse rate is as high as 50%; therefore, prolonged treatment may be emphasized. We have described a child with acute myeloid leukemia (AML), that developed skin lesions and asymptomatic chronic meningitis, with a good evolution after prolonged treatment with amphotericin B deoxycholate followed by fluconazole.

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Bibliographic Details
Main Authors: Pereira,G.H., Pádua,S.S., Park,M.V.F., Muller,R.P., Passos,R.M.A., Menezes,Y.
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2008
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000600026
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