Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg

The obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce seedlings were obtained through the application of a regulated balance of plant growth regulators. Genetic transformation process was acquired by cocultivation of cotyledons with Agrobacterium tumefaciens harboring the recombinant plasmid. It is the first description of a lettuce Brazilian variety "Vitória de Verão" genetically modified.

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Bibliographic Details
Main Authors: Marcondes,Jackson, Hansen,Ekkehard
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2008
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000600004
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