Risk factors for three-vessel coronary artery disease in patients of Northwest Mexico

Abstract Introduction: Three-vessel coronary artery disease is an advanced manifestation of atherosclerosis, with high prevalence in Mexico. Objective: The aim of this study was to describe coronary risk factors in a group of patients with three-vessel coronary artery disease in Northwest Mexico. Methods: A cross sectional study was conducted on a population with three-vessel coronary artery disease from May 2015 to February 2016. The disease was defined when ≥70% stenosis was present in each major epicardial coronary artery. Anthropometric and biochemical parameters were measured in each patient. Ankle-Brachial Index was measured with vascular ultrasound, and Syntax score calculation with an on-line application. Statistical analysis for qualitative differences was performed using Pearson X2 test, with p < 0.05 being considered as significant. Results: The study included 100 patients, of whom 75 were male (mean age 63 ± 9 years) and 25 female (mean age 69 ± 9 years). The coronary risk factors observed were diabetes (58%), hypertension (86%), smoking (68%), dyslipidaemia (100%), metabolic syndrome (71%), and obesity/overweight (75%). Diabetes and metabolic syndrome prevalence was higher in women (p = 0.03), but smoking was higher in men (76%, p = 0.003). Ankle-Brachial Index was abnormal in 58% of patients, the mean Syntax score was in 36.9 ± 11.5, and the prevalence of left main coronary heart disease was 36%. Conclusions: This group of patients with complex coronary lesions has a high prevalence of coronary risk factors, which could represent a worse prognosis.

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Bibliographic Details
Main Authors: Arroyo-Rodríguez,Cuitlahuac, Brito-Zurita,Olga Rosa, Sandoval-Navarrete,Santiago, Solis-Vásquez,Rogelio, Ornelas-Aguirre,José Manuel, Olea-Hernández,Celestino, Vásquez-Serna,César, Castelan-Ojeda,Amanda Marcela
Format: Digital revista
Language:English
Published: Instituto Nacional de Cardiología Ignacio Chávez 2018
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-99402018000500423
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