Infiltrating gastric adenocarcinoma with disseminated osteoblastic metastases

We report the case of a man with a diagnosis of invasive gastric adenocarcinoma associated with scattered osteoblastic metastases. This 65-year-old patient was admitted with nausea, vomiting and abdominal pain, in addition to loss of weight (13 Kg in 3 months). Upper digestive endoscopy revealed extensive infiltrating changes in the body of the stomach, and histopathologic data confirmed the diagnosis of a Borrmann IV gastric adenocarcinoma. Complementary exams were indicative of a gastric cancer with bone metastases, characterized by disseminated osteoblastic images of the scintigraphy of the skeleton. Palliative chemotherapy was the treatment of first choice. High serum levels of CA 19-9, CEA and alkaline phosphatase can constitute useful indicative tools of this challenging condition. Images from a scintigraphy study of the skeleton can characterize the type and extension of bone metastases. The aim of this case study is to report a case of a very uncommon condition, considering that disseminated osteoblastic metastases rarely develop in this kind of tumor.

Saved in:
Bibliographic Details
Main Authors: Santos,V.M., Vieira,T.A., Marinho,C.S., Loures,T.P., Brandao,B.B.V., Botan,R.N.
Format: Digital revista
Language:English
Published: Gobierno de Navarra. Departamento de Salud 2013
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1137-66272013000100022
Tags: Add Tag
No Tags, Be the first to tag this record!