Differential Pulse Anodic Voltammetric Determination of the Pharmaceutical Compound Pramipexole Dihydrochloride in its Tablets
The electrochemical behavior of pramipexole dihydrochloride was studied at carbon paste electrodes in 0.04 M Britton-Robinson buffer of pH 6.08, using cyclic and differential pulse voltammetric techniques. The oxidation of pramipexole dihydrochloride is an irreversible diffusion-controlled process. A differential pulse anodic voltammetric procedure has been developed for determination of the drug over the concentration range of 1.20 - 8.23 μg/mL, with detection and quantification limits of 0.21 and 0.68 μg/mL, respectively. The proposed method was successfully applied for the determination of the drug in its commercial tablets.
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| Main Authors: | , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedade Portuguesa de Electroquímica
2017
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| Online Access: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042017000500005 |
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