Immune dysfunction in chronic kidney disease

ABSTRACT Chronic kidney disease is characterized by immune dysfunction that increases predisposition to infections, virus-associated cancers and impaired response to vaccination. The altered immune response is caused by impairment of both innate and adaptive immune systems, as well as other factors that are hallmarks of renal disease, such as uremia, malnutrition, chronic inflammation, mineral bone disease and anemia. The aim of this article is to review the causes and mechanisms that lead to immune dysfunction in patients with chronic kidney disease.

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Main Authors: Fernandes,Sara Cardoso, Ferreira,Ana Carina
Format: Digital revista
Language:English
Published: Sociedade Portuguesa de Nefrologia 2021
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692021000400247
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spelling oai:scielo:S0872-016920210004002472022-01-25Immune dysfunction in chronic kidney diseaseFernandes,Sara CardosoFerreira,Ana Carina Immune dysfunction chronic kidney disease uremia ABSTRACT Chronic kidney disease is characterized by immune dysfunction that increases predisposition to infections, virus-associated cancers and impaired response to vaccination. The altered immune response is caused by impairment of both innate and adaptive immune systems, as well as other factors that are hallmarks of renal disease, such as uremia, malnutrition, chronic inflammation, mineral bone disease and anemia. The aim of this article is to review the causes and mechanisms that lead to immune dysfunction in patients with chronic kidney disease.info:eu-repo/semantics/openAccessSociedade Portuguesa de NefrologiaPortuguese Journal of Nephrology & Hypertension v.35 n.4 20212021-12-01info:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692021000400247en10.32932/pjnh.2021.12.159
institution SCIELO
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country Portugal
countrycode PT
component Revista
access En linea
databasecode rev-scielo-pt
tag revista
region Europa del Sur
libraryname SciELO
language English
format Digital
author Fernandes,Sara Cardoso
Ferreira,Ana Carina
spellingShingle Fernandes,Sara Cardoso
Ferreira,Ana Carina
Immune dysfunction in chronic kidney disease
author_facet Fernandes,Sara Cardoso
Ferreira,Ana Carina
author_sort Fernandes,Sara Cardoso
title Immune dysfunction in chronic kidney disease
title_short Immune dysfunction in chronic kidney disease
title_full Immune dysfunction in chronic kidney disease
title_fullStr Immune dysfunction in chronic kidney disease
title_full_unstemmed Immune dysfunction in chronic kidney disease
title_sort immune dysfunction in chronic kidney disease
description ABSTRACT Chronic kidney disease is characterized by immune dysfunction that increases predisposition to infections, virus-associated cancers and impaired response to vaccination. The altered immune response is caused by impairment of both innate and adaptive immune systems, as well as other factors that are hallmarks of renal disease, such as uremia, malnutrition, chronic inflammation, mineral bone disease and anemia. The aim of this article is to review the causes and mechanisms that lead to immune dysfunction in patients with chronic kidney disease.
publisher Sociedade Portuguesa de Nefrologia
publishDate 2021
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692021000400247
work_keys_str_mv AT fernandessaracardoso immunedysfunctioninchronickidneydisease
AT ferreiraanacarina immunedysfunctioninchronickidneydisease
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