Hypersensitivity reaction to Patent Blue Dye

ABSTRACT Patent Blue Dye (PBD) is a synthetic blue dye commonly used in medical practice for sentinel lymph node mapping in breast cancer. The authors report the case of a patient with invasive ductal carcinoma of the left breast, who underwent unilateral mastectomy with sentinel lymph node mapping. During surgery, the patient developed violaceous urticaria and mild glottic edema. A hypersensitivity reaction to PBD was confirmed by skin prick tests and methylene blue was identified as a possible alternative dye. This article reinforces the need for greater awareness of the possible hypersensitivity reactions to PBD during surgical procedures.

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Bibliographic Details
Main Authors: Presa,Ana R., Garcia,Sónia, Cadinha,Susana, Sousa,Maria João
Format: Digital revista
Language:English
Published: Sociedade Portuguesa de Alergologia e Imunologia Clínica 2023
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S0871-97212023000200163
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