Alternative Oral Mucous Membrane Pemphigoid Therapy Using Tacrolimus: A Case Report

ABSTRACT: Mucous membrane pemphigoid (MMP) is a blistering disease that predominantly involves the mucous membranes and that can lead to major negative impacts on patient quality of life. The first-line MMP treatment is based on the use of topical and systemic corticosteroids. In this report, we presented a 45-year-old female patient presented blisters in the inferior gingiva for over 8-months. The patient reported being allergic to corticosteroids. Under the clinical hypothesi s of oral lichen planus and MMP, an incisional biopsy was performed, and the histopathological diagnosis of MMP was established. Thus, it was instituted an alternative therapy with tacrolimus 0.03 %. The patient showed an excellent clinical outcome with no recurrence five months after the end of therapy. Tacrolimus 0.03 % may represent an effective therapeutic alternative in MMP treatment and may be used in cases of hypersensitivity to standard therapy.

Bibliographic Details

Main Authors:	da Silva Barros,Caio César, Leal Cavalcante,Israel, Bastos Leite,Rafaella, Dantas da-Silveira,Éricka Janine, Costa de Medeiros,Ana Miryam, Teixeira de Oliveira,Patricia
Format:	Digital revista
Language:	English
Published:	Universidad de La Frontera. Facultad de Medicina 2021
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2021000400904
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