Genetic Autosomal Dominant Disorders: A Knowledge Review

Genetic disorders occur by excess or absence of chromosomal material, and the consequence of these changes is reflected in morphological and physiological changes. Autosomal disorders, which have dominant inheritance, as cleidocranial dysostosis, Craniofacial syndrome Apert, Treacher Collins and Achondroplasia have peculiar and similar characteristics. Because of their implications in the dental field, the aim of this review is to report on dysostoses, through exposure of general clinical factors and highlighting the signs in the oral cavity. Articles were selected from Lilacs, PubMed and Bireme databases, included in the year 2007­2014, and the keywords were: cleidocranial dysplasia, craniofacial dysostosis, mandibulofacial dysostosis, dysostosis and oral. Alterations of maxillofacial bones and craniofacial are well documented in the literature, but studies reporting an association between treatment odontologic and dysostoses are scarce. In conclusion, Oral pathological manifestations developed cause difficulty in speech, chewing, breathing, social involvement, and in a general perspective, psychological impairment and physical limitations.

Bibliographic Details

Main Authors:	Nogueira,Brenna Magdalena Lima, Silva,Tayana Nascimento da, Nogueira,Bárbara Catarina Lima, da Silva,Walessa Brasil, Menezes,Silvio Augusto Fernandes de, Menezes,Tatiany Oliveira de Alencar
Format:	Digital revista
Language:	English
Published:	Universidad de La Frontera. Facultad de Medicina 2015
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2015000100023
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