SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST
ABSTRACT In this study, the synthesis of new coumarins with aliphatic chains is discussed. The incorporation of the 6- tert -octyl and 6,8-di tert -butyl chains into a coumarin structure from alkylphenols, allows obtaining hydrophobic coumarins with good yields. These coumarins can be potential modulators of TRPV1 receptors. Synthesis and spectroscopic data of these new coumarins are analyzed.
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| Main Authors: | , , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedad Chilena de Química
2021
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| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072021000205220 |
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