CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA

CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA

The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunohde and liriodenine with cytotoxic activities, along with the isolation of twenty-seven known compounds. The active costunohde existed as major constituent in this study.

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Bibliographic Details
Main Authors: LIU,CHIA-YUAN, CHEN,YANG-WEN, CHENG,MING-JEN, LEE,SHOIW-JU, ABD EL-RAZEK,MOHAMED H, CHANG,WEN-HSIUNG, CHEN,YU-JEN, CHEN,IH-SHENG
Format: Digital revista
Language:English
Published: Sociedad Chilena de Química 2008
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000200017
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