Celecoxib: Antiangiogenic and Antitumoral Action

SUMMARY: Angiogenesis, a process by which new blood vessels are generated from pre-existing ones, is significantly compromised in tumor development, given that due to the nutritional need of tumor cells, pro-angiogenic signals will be generated to promote this process and thus receive the oxygen and nutrients necessary for its development, in addition to being a key escape route for tumor spread. Although there is currently an increase in the number of studies of various anti-angiogenic therapies that help reduce tumor progression, it is necessary to conduct a review of existing studies of therapeutic alternatives to demonstrate their importance.

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Bibliographic Details
Main Authors: Rojas,V, Roa,I
Format: Digital revista
Language:English
Published: Sociedad Chilena de Anatomía 2024
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022024000100040
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