The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor

The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor

SUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.

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Bibliographic Details
Main Authors: Simões,Luciana Senna, Sasahara,Taís Harumi de Castro, Favaron,Phelipe Oliveira, Leal,Leonardo Martins, Oliveira,Fabrício Singaretti de, Fratini,Paula, Berger,Trish, Machado,Marcia Rita Fernandes, Miglino,Maria Angélica
Format: Digital revista
Language:English
Published: Sociedad Chilena de Anatomía 2020
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000601525
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