Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2)
Seven compounds were synthesized as potential anti-inflammatory drugs, selective inhibitors of the enzyme cyclooxygenase-2 (COX-2). The structural design was based on the knowledge of the active site of the enzyme. The synthesized compounds present a combined naproxen and celecoxib structures.
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Sociedad Química de México A.C.
2004
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oai:scielo:S0583-769320040004000042017-02-25Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2)Guzmán,AngelDíaz,EduardoTrejo,Blanca E.López-Muñoz,Francisco J. Cyclooxygenase anti-inflammatory drugs naproxen celecoxib synthesis Seven compounds were synthesized as potential anti-inflammatory drugs, selective inhibitors of the enzyme cyclooxygenase-2 (COX-2). The structural design was based on the knowledge of the active site of the enzyme. The synthesized compounds present a combined naproxen and celecoxib structures.info:eu-repo/semantics/openAccessSociedad Química de México A.C.Revista de la Sociedad Química de México v.48 n.4 20042004-12-01info:eu-repo/semantics/articletext/htmlhttp://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0583-76932004000400004en |
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México |
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MX |
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rev-scielo-mx |
| tag |
revista |
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America del Norte |
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| language |
English |
| format |
Digital |
| author |
Guzmán,Angel Díaz,Eduardo Trejo,Blanca E. López-Muñoz,Francisco J. |
| spellingShingle |
Guzmán,Angel Díaz,Eduardo Trejo,Blanca E. López-Muñoz,Francisco J. Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2) |
| author_facet |
Guzmán,Angel Díaz,Eduardo Trejo,Blanca E. López-Muñoz,Francisco J. |
| author_sort |
Guzmán,Angel |
| title |
Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2) |
| title_short |
Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2) |
| title_full |
Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2) |
| title_fullStr |
Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2) |
| title_full_unstemmed |
Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2) |
| title_sort |
synthesis of potential anti-inflammatory compounds, selective inhibitors of cyclooxygenase-2 (cox-2) |
| description |
Seven compounds were synthesized as potential anti-inflammatory drugs, selective inhibitors of the enzyme cyclooxygenase-2 (COX-2). The structural design was based on the knowledge of the active site of the enzyme. The synthesized compounds present a combined naproxen and celecoxib structures. |
| publisher |
Sociedad Química de México A.C. |
| publishDate |
2004 |
| url |
http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0583-76932004000400004 |
| work_keys_str_mv |
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| _version_ |
1756224861207789568 |