Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2)
Seven compounds were synthesized as potential anti-inflammatory drugs, selective inhibitors of the enzyme cyclooxygenase-2 (COX-2). The structural design was based on the knowledge of the active site of the enzyme. The synthesized compounds present a combined naproxen and celecoxib structures.
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| Main Authors: | , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedad Química de México A.C.
2004
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| Online Access: | http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0583-76932004000400004 |
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