![(±)-Bocconarborines A and B, Novel 1,3-Bis-Benzo[c]phenanthridinyl Acetone Alkaloids from Bocconia arborea](/search/themes/bootstrap3/images/revista.png)
(±)-Bocconarborines A and B, Novel 1,3-Bis-Benzo[c]phenanthridinyl Acetone Alkaloids from Bocconia arborea
Chemical examination of the aerial parts of Bocconia arborea (Papaveraceae), a plant used in traditional medicine, led to the characterization of (±)-6-acetonyldihydrosanguinarine (1), (±)-6-acetonyldihydrochelerythrine (2), (±)-6-methoxydihydrochelerythrine (3), (±)-sanguidimerine (4), chelidimerine (5), and the novel constituents (±)-bocconarborine A ((6R,6'S + 6S,6'R)-13-(6-hydrosanguinarinyl)-15-(6'-hydrochelerythrinyl)-acetone, 6) and (±)-bocconarborine B ((6R,6'R + 6S,6'S)-13-(6-hydrosanguinarinyl)-15-(6'-hydrochelerythrinyl)-acetone, 7). The structure and stereochemistry of the novel structures were determined by analyzing the preferred conformations and the spectroscopic data. Antimicrobial evaluations revealed that 3 exhibited activity against S. aureus, S. faecalis and C. albicans.
| Main Authors: | , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedad Química de México A.C.
2001
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| Online Access: | http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0583-76932001000400010 |
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