New Bioactive Derivatives of Xanthorrhizol

The chemical preparation and the antifungic and cytotoxic evaluations of several new derivatives of xanthorrhizol, a bioactive natural product isolated from certain plants used in traditional medicine, are described. Acylation of the phenol, bromination of the benzene ring, as well as reduction and oxidation of the olefin of the natural sesquiterpene, allowed obtaining a series of derivatives which displayed mild antifungic activities and did not show cytotoxic activities toward certain human tumor cell lines.

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Bibliographic Details
Main Authors: Aguilar,María Isabel, Delgado,Guillermo, Villarreal,María Luisa
Format: Digital revista
Language:English
Published: Sociedad Química de México A.C. 2001
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0583-76932001000200004
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