Chimo, a smokeless tobacco preparation, is associated with a higher frequency of type 2 diabetes

The relationship between smokeless tobacco (ST) use and type-2 diabetes (T2D) has only been reported in Swedish men, though with contradictory results. In Venezuela, chimó is the most common ST preparation. The relationship between chimó and T2D in Venezuela is unknown. The objective of the study was to evaluate the relationship between chimó use and T2D in a population with high prevalence of ST use in the Andes region of Venezuela. An observational, cross-sectional, correlational study was designed. During 2013-2014, 759 consecutive subjects aged 20 years or older were evaluated in a medical center. Anthropometric measurements and responses to a standard questionnaire were obtained. Blood glucose and lipid concentrations were measured. The mean age was 53.1 years, 58% were female, and 24.1% reported ST use. ST use was more frequent in men than women (32.9% vs. 17.7%; p < 0.001). ST users showed lower body mass index (BMI), body fat and total cholesterol, but a higher frequency of T2D, than non-ST users. Logistic regression analysis, adjusted by age, family history of T2D, and hypertriglyceridemia, demonstrated that ST use was associated with an increased odd for T2D by 77% (OR 1.77; 95% CI 1.15 - 2.72) among ST-users. In conclusion, chimó, a ST form frequently used in the Andes region of Venezuela, is associated with a higher frequency of T2D and lower fat mass. Implications of these findings are discussed.

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Bibliographic Details
Main Authors: González-Rivas,Juan P, Nieto-Martínez,Ramfis, García Santiago,Raúl, Ugel,Eunice, Mechanick,Jeffrey I
Format: Digital revista
Language:English
Published: Instituto de Investigaciones Clínicas "Dr. Américo Negrette", Facultad de Medicina, Universidad del Zulia 2017
Online Access:http://ve.scielo.org/scielo.php?script=sci_arttext&pid=S0535-51332017000300004
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